From WikiLectures

Craniopharyngioma is the second most common tumor in the selar region (the first is pituitary adenoma). It represents about 4% of intracranial tumors, 50% of them in children - most often between 10-15. year. It grows out of the remnants of Rathke's cysts, often reaching high into III. ventricle of the brain. The tumor is biologically benign, but may be malignant due to its location and relationship to vital structures such as the hypothalamus, blood vessels, optic chiasm.

Histological specimen

It almost always has two components - solid and cystic.

Clinical picture[edit | edit source]

Diagnosis[edit | edit source]

  • MRI.
  • CT – bounded formation with calcifications.

Differential diagnosis[edit | edit source]

It is facilitated by the fact that, unlike adenomas they are usually cystic and calcified.

Therapy[edit | edit source]

  • Primarily surgical – usually subfrontally, compared to adenomas, it is removed much worse because it fuses with the formations around. Therefore, the operation is often not radical and the tumor recurs (it can be irradiated, but in children it is complicated).
  • Radiotherapy – we completely irradiate incompletely removed tumors with small fields, which are targeted only at the tumor area. The total dose is about 50-55 Gy in 5-6 weeks.

Link[edit | edit source]

related articles[edit | edit source]

Source[edit | edit source]

REferences[edit | edit source]

  • ZEMAN, Miroslav, et al. Speciální chirurgie. 2. edition. Praha : Galén, 2004. 575 pp. ISBN 80-7262-260-9.
  • SAMEŠ,, et al. Neurochirurgie : Učebnice pro lékařské fakulty a postgraduální studium příbuzných oborů. 1. edition. Praha : Maxdorf, 2005. 127 pp. pp. 79. ISBN 80-7345-072-0.
  • PETRUŽELKA, Luboš – KONOPÁSEK, Bohuslav. Klinická onkologie. 1. edition. Praha : Karolinum, 2003. 274 pp. ISBN 80-246-0395-0.

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