Non-epithelial tumors of the ovary
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Nonepithelial ovarian tumors can be either tumors of germ cell or tumors of stromal and germline cells' (sex cord- gonadal stromal tumors).
Germ cell tumors[edit | edit source]
For more information see Germinal tumors.There can be purely germline tumors and tumors mixed with germline tumors. Purely germinal can be[1]:
- dysgerminoma - is the most common malignant germinal tumor and affects both ovaries in 20%, is chemo and radiosensitive (treated with chemotherapy); there is a high risk of developing malignant dysgerminoma in any (phenotypic) woman with a 46,XY karyotype or the presence of SRY - this is an indication for removal of the gonads[2];
- yolk sac tumor;
- embryonic carcinoma;
- polyembrome;
- choriocarcinoma;
- teratoma.
Sex cord-gonadal stromal tumors[edit | edit source]
They may be of germline tissue or stromal tissue or both (mixed) and may produce either estrogens, androgens or both (gynandroblastoma). They are distinguished by:
- granulosa tumors;
- thecomas/fibromas;
- androblastomas (Sertoli tumor, Leydig tumor, Sertoli-Leydig tumor);
- gynandroblastomas (mixed male and female, may be mixed stromal and sex-cord, or one of these tissues).
Links[edit | edit source]
Source[edit | edit source]
Related Articles[edit | edit source]
External links[edit | edit source]
- www.onkogyn.cz
- Sex cord-gonadal stromal tumor (English Wikipedia page)
