Ferritin

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"Ferritin" is a storage protein containing iron, which is found mainly in the liver, spleen, bone marrow and intestinal mucosa. A small proportion is released into the bloodstream. The level of ferritin in the blood serum reflects the tissue stores of iron. Its value decreases before the level of transferrin u increases. ^[1]

It is a complex consisting of the protein apoferritin em and the ferric iron Fe ³⁺. ^[2]

Normal values of ferritin[edit | edit source]

Males: 22 - 322 μg / l
Women: 10 - 291 μg / l ^[3]

High Iron level[edit | edit source]

Hemochromatosis,
Wilson's disease,
Blood transfusion,
Excessive iron intake in the diet,
Porphyria cutanea tarda,
Ineffective erythropoiesis (sideroblastic anemia, thalassemia).

Inflammation[edit | edit source]

Ferritin is one of the acute phase reactants

Liver disease[edit | edit source]

Ferritin is stored mainly in hepatocytes, when they are damaged it is released into the blood.

liver steatosis (NASH),
viral hepatitis B, C;

Other causes[edit | edit source]

Obesity, alcohol abuse, thyrotoxicosis and malignancies, especially haematological ^[4] Rarely, extremely high levels of ferritin can be a symptom of histiocytosis or Still's disease. ^[5]

Links[edit | edit source]

External links[edit | edit source]

References[edit | edit source]

↑ {{#switch: book isbn = 80-7262-023-1 |book = Incomplete publication citation. SEAGULL, J, et al. Clinical Biochemistry issue = First. Prague publisher = Galén - Karolinum. 1999. pp. 64. |collection = Incomplete citation of contribution in proceedings. SEAGULL, J, et al. Clinical Biochemistry issue = First. Prague publisher = Galén - Karolinum. 1999. pp. 64. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. SEAGULL, J, et al. 1999, year 1999, pp. 64, |web = Incomplete site citation. SEAGULL, J, et al. ©1999. |cd = Incomplete carrier citation. SEAGULL, J, et al. ©1999. |db = Incomplete database citation. ©1999. |corporate_literature = Incomplete citation of company literature. SEAGULL, J, et al. Clinical Biochemistry issue = First. Prague publisher = Galén - Karolinum. 1999. legislative_document = Incomplete citation of legislative document. 1999. s. 64.
↑ {{#switch: web |book = Incomplete publication citation. ŠVÍGLEROVÁ, JitkaAlso available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |collection = Incomplete citation of contribution in proceedings. ŠVÍGLEROVÁ, Jitka. Also available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. ŠVÍGLEROVÁ, Jitka. Ferritin. also available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |web = ŠVÍGLEROVÁ, Jitka. Ferritin [online]. [cit. 2010-11-13]. <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |cd = ŠVÍGLEROVÁ, Jitka. Ferritin [CD/DVD]. [cit. 2010-11-13]. |db = Incomplete database citation. Ferritin [database]. [cit. 2010-11-13]. <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |corporate_literature = Incomplete citation of company literature. ŠVÍGLEROVÁ, Jitka. Also available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. legislative_document = Incomplete citation of legislative document. Also available from URL <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>.
↑ {{#switch: book surname1 = Vokurka |book = Incomplete publication citation. . Great Medical Dictionary issue = 10. Maxdorf, 2015. 978-80-7262-438-6. |collection = Incomplete citation of contribution in proceedings. . Great Medical Dictionary issue = 10. Maxdorf, 2015. {{ #if: 9788073454562 |978-80-7262-438-6} } |article = Incomplete article citation. . 2015, year 2015, |web = Incomplete site citation. . Maxdorf, ©2015. |cd = Incomplete carrier citation. . Maxdorf, ©2015. |db = Incomplete database citation. Maxdorf, ©2015. |corporate_literature = . Great Medical Dictionary issue = 10. Maxdorf, 2015. 978-80-7262-438-6} }
↑ {{#switch: article surname1 = Berkhan |book = Incomplete publication citation. 2002. pp. 45-48. Also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |collection = Incomplete citation of contribution in proceedings. . 2002. pp. 45-48. Also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. . Interpretation of an elevated serum ferritin magazine = nzfp. 2002, year 2002, pp. 45-48, also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |web = Incomplete site citation. . ©2002. <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |cd = Incomplete carrier citation. . ©2002. |db = Incomplete database citation. ©2002. <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |corporate_literature = Incomplete citation of company literature. . 2002. Also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. legislative_document = Incomplete citation of legislative document. 2002. s. 45-48. Also available from URL <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. ISSN -.
↑ {{#switch: article surname1 = Adams |book = Incomplete publication citation. -. pp. 333-334. Also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |collection = Incomplete citation of contribution in proceedings. . -. pp. 333-334. Also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. . Management of Elevated Serum Ferritin Levels. -, year -, pp. 333-334, also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |web = Incomplete site citation. . ©-. <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |cd = Incomplete carrier citation. . ©-. |db = Incomplete database citation. ©-. <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |corporate_literature = Incomplete citation of company literature. . -. Also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. legislative_document = Incomplete citation of legislative document. -. s. 333-334. Also available from URL <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. ISSN -.

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[1] {{#switch: book isbn = 80-7262-023-1 |book = Incomplete publication citation. SEAGULL, J, et al. Clinical Biochemistry issue = First. Prague publisher = Galén - Karolinum. 1999. pp. 64. |collection = Incomplete citation of contribution in proceedings. SEAGULL, J, et al. Clinical Biochemistry issue = First. Prague publisher = Galén - Karolinum. 1999. pp. 64. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. SEAGULL, J, et al. 1999, year 1999, pp. 64, |web = Incomplete site citation. SEAGULL, J, et al. ©1999. |cd = Incomplete carrier citation. SEAGULL, J, et al. ©1999. |db = Incomplete database citation. ©1999. |corporate_literature = Incomplete citation of company literature. SEAGULL, J, et al. Clinical Biochemistry issue = First. Prague publisher = Galén - Karolinum. 1999. legislative_document = Incomplete citation of legislative document. 1999. s. 64.

[2] {{#switch: web |book = Incomplete publication citation. ŠVÍGLEROVÁ, JitkaAlso available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |collection = Incomplete citation of contribution in proceedings. ŠVÍGLEROVÁ, Jitka. Also available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. ŠVÍGLEROVÁ, Jitka. Ferritin. also available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |web = ŠVÍGLEROVÁ, Jitka. Ferritin [online]. [cit. 2010-11-13]. <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |cd = ŠVÍGLEROVÁ, Jitka. Ferritin [CD/DVD]. [cit. 2010-11-13]. |db = Incomplete database citation. Ferritin [database]. [cit. 2010-11-13]. <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. |corporate_literature = Incomplete citation of company literature. ŠVÍGLEROVÁ, Jitka. Also available from <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>. legislative_document = Incomplete citation of legislative document. Also available from URL <https: //web.archive.org/web/20160416225121/http: //wiki.lfp-studium.cz/index.php/Feritin>.

[3] {{#switch: book surname1 = Vokurka |book = Incomplete publication citation. . Great Medical Dictionary issue = 10. Maxdorf, 2015. 978-80-7262-438-6. |collection = Incomplete citation of contribution in proceedings. . Great Medical Dictionary issue = 10. Maxdorf, 2015. {{ #if: 9788073454562 |978-80-7262-438-6} } |article = Incomplete article citation. . 2015, year 2015, |web = Incomplete site citation. . Maxdorf, ©2015. |cd = Incomplete carrier citation. . Maxdorf, ©2015. |db = Incomplete database citation. Maxdorf, ©2015. |corporate_literature = . Great Medical Dictionary issue = 10. Maxdorf, 2015. 978-80-7262-438-6} }

[4] {{#switch: article surname1 = Berkhan |book = Incomplete publication citation. 2002. pp. 45-48. Also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |collection = Incomplete citation of contribution in proceedings. . 2002. pp. 45-48. Also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. . Interpretation of an elevated serum ferritin magazine = nzfp. 2002, year 2002, pp. 45-48, also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |web = Incomplete site citation. . ©2002. <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |cd = Incomplete carrier citation. . ©2002. |db = Incomplete database citation. ©2002. <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. |corporate_literature = Incomplete citation of company literature. . 2002. Also available from <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. legislative_document = Incomplete citation of legislative document. 2002. s. 45-48. Also available from URL <http://www.rnzcgp.org.nz/AsiCommon/Controls/Shared/FormsAuthentication/Login.aspx?ReturnUrl=%2fassets%2fdocuments%2fPublications%2fArchive-NZFP%2fFeb-2002-NZFP-Vol-29-No -1% 2fberkhan.pdf>. ISSN -.

[5] {{#switch: article surname1 = Adams |book = Incomplete publication citation. -. pp. 333-334. Also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |collection = Incomplete citation of contribution in proceedings. . -. pp. 333-334. Also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. {{ #if: |978-80-7262-438-6} } |article = Incomplete article citation. . Management of Elevated Serum Ferritin Levels. -, year -, pp. 333-334, also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |web = Incomplete site citation. . ©-. <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |cd = Incomplete carrier citation. . ©-. |db = Incomplete database citation. ©-. <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. |corporate_literature = Incomplete citation of company literature. . -. Also available from <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. legislative_document = Incomplete citation of legislative document. -. s. 333-334. Also available from URL <https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC3093720/>. ISSN -.

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