Antithrombotics
From WikiLectures
Antithrombotic mechanisms:
Antithrombotics are substances that reduce blood clotting.
- Anticoagulants - reduce blood clotting by affecting the production and effects of coagulation factors.
- Direct - heparin and low molecular weight heparins - act as catalytic cofactors of antithrombin III and inhibit some serine proteases coagulation cascades.
- Indirect - oral anticoagulants (coumarol derivatives - warfarin, pelentan) - inhibit the functions of vitamin K.
- Antiplatelet agents – prevent the formation of a thrombus by inhibiting the functions of platelets – e.g. acetylsalicylic acid.
- Thrombolytics – dissolve the formed thrombus, include fibrinolytics – e.g. streptokinase.
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Source[edit | edit source]
- PASTOR, Jan. Langenbeck's medical web page [online]. ©2006. [cit. 2011-10-22]. <https://langenbeck.webs.com/>.
