Non-epithelial ovarian tumors
From WikiLectures
Non-epithelial ovarian tumors can be either germ cell tumors, or stromal and germ cell tumors (sex cord-gonadal stromal tumors).
Germinal tumorsy[edit | edit source]
The tumors may be purely germinal and tumors mixed with germline tumors. Purely germinal can be[1]:
- dysgerminoma – is the most common malignant germ cell tumor and in 20% it affects both ovaries, t is chemo and radiosensitive (it is treated with chemotherapy); every (phenotypic) woman with karyotype 46, XY or the presence of SRY – is at high risk of developing malignant dysgerminoma - this is an indication to remove gonads[2];
- yolk sac tumor;
- embryonic carcinoma;
- polyembrom;
- choriokarcinom;
- teratom.
Sex cord-gonadal stromal tumors[edit | edit source]
They can be from germline tissue, or from stromal tissue, or both (mixed ), and can produce either estrogens, androgens, or both ( gynandroblastoma ). They are distinguished as follows::
- granulosa tumors;
- thekomy/fibromy;
- androblastomas (Sertoli tumor, Leydig tumor, Sertoli-Leydig tumor);
- gynandroblastomas (mixed male and female, can be mixed stromal and sex-cord, or one of these tissues).
Links[edit | edit source]
Related articles[edit | edit source]
External links[edit | edit source]
- www.onkogyn.cz
- Sex cord-gonadal stromal tumour (wikipedia page)
