Nephrogenic diabetes insipidus
From WikiLectures
Nephrogenic diabetes insipidus is a rare inherited disease linked to the chromosome X (mutation vasopressin receptor gene or aquaporin 2 gene).
- Acquired form much more common: may occur in patients with nephropathy affecting the marrow kidneys + distal tubules ( polycystic kidney disease | polycystic kidney disease, chronic pyelonephritis, etc.), when administration of certain drugs (Li);
- inability of tubular cells to respond to ADH (normal blood concentration).
Clinical symptoms[edit | edit source]
Diagnostics[edit | edit source]
- Dg. determined using a concentration test with exogenous ADH.
Therapy[edit | edit source]
- Adequate fluid intake;
- restrictions Na in the diet, hydrochlorothiazide / indomethacin.
Links[edit | edit source]
Related articles[edit | edit source]
References[edit | edit source]
Kategorie:Vnitřní lékařství Kategorie:Nefrologie Kategorie:Endokrinologieno
