Infectious mononucleosis syndrome
Infectious mononucleosis syndrome is a disease that is clinically very similar to infectious mononucleosis, but does not meet all laboratory criteria and is characterized by a lack of heterophile antibodies. Clinically, it manifests as cervical lymphadenopathy followed by other symptoms that are less common (such as throat-related findings, hepatosplenomegaly).
- Causative agents
- human Cytomegalovirus,
- rarely HIV, rubeola virus, adenoviruses, Toxoplasma gondii, HHV-6 and HHV-7 .
Source, transmission and incubation period depend on the causative agent. We determine the diagnosis based upon lymphadenopathy, atypical lymphocytes in peripheral blood, increase in aminotransferases enzymes in the blood without increase in lactate dehydrogenase at the same time and serological evidence of the causative agent. The prognosis is good, we are able to treat the symptoms (rest and liver disease diet).
|CRITERIA||Infectious mononucleosis||Infectious mononucleosis syndrome|
|Agens||EBV (Epstein-Barr virus)||CMV, HIV, rubeola, toxoplasma|
|Hepatic syndrome||✔||could be present|
|Throat-related findings||✔||could be present|
Source[edit | edit source]
- ROZSYPAL, Hanuš. Základy infekčního lékařství. 1. edition. Praha : Karolinum, 2015. 566 pp. ISBN 978-80-246-2932-2.