Therapy of diarrheal diseases

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  • We start the therapy immediately, the initial therapy is always the same.
  • Adjustment of water and mineral metabolism is necessary.
  • For milder toxoinfections, this adjustment of metabolism is usually sufficient.
  • Tea is also served, slightly sweetened, or mineral water without bubbles.
  • WHO Rehydration Solution.
H2O 1 liter
NaCl 3,5 g
NaHCO3 2,5 g
KCl 1,5 g
glucose 20 g
  • Valík's solution – for children, it contains more glucose, less K and Na.
  • For home preparation we need 4 tablespoons of sugar, 1 teaspoon of baking soda, ¾ teaspoons of salt, a cup of orange juice and than we add to all this water to 1 liter.
  • Severe course with vomiting – nasogastric tube is used in infants, in adults – i. v.
  • ATB do not use unless we have a causal diagnosis.
  • We use Endiaron as a disinfectant – 3-6 tablets a day, we do not take it for more than 5-7 days.
  • Adsorption – coal is usually without effect.
  • Do not use antispasmodics and antimotilics.

Use of antibiotics[edit | edit source]

  • Controversial effect, it is necessary to CONSIDER treatment: they reduce the number of microbes, they do not usually affect the duration of the disease, the length of microbial excretion.
  • If bakteremia occurs – ATBs are indicated, as a prevention of sepsis and metastatic inflammatory lesions (organ absceses).

The choice of antibiotics:

  • ETEC – cotrimoxazole, trimethoprim;
  • EPEC – cotrimoxazole;
  • EHEC – cotrimoxazole;
  • Shigella – cotrimoxazole, ampicillin (amoxicillin is ineffective), quinolones;
  • Campylobacter – fluoroquinolones, erythromycin;
  • Salmonella – cotrimoxazole, fluoroquinolones;
  • Vibrio cholerae – furazolidone (resistance is very rarely), doxycycline, cotrimoxazole, erythromycin, norfloxacin;
  • Clostridium difficile – metronidazole, vancomycin, teicoplanin.

Links[edit | edit source]

Related articles[edit | edit source]

Sources[edit | edit source]

  • BENEŠ, Jiří. Studijní materiály [online]. ©2010. [cit. 2010]. <>.

References[edit | edit source]

  • HAVLÍK, Jiří, et al. Infektologie. 2. edition. Praha : Avicenum, 1990. pp. 393. ISBN 80-201-0062-8.
  • LOBOVSKÁ, Alena. Infekční nemoci. 1. edition. Praha : Karolinum, 2001. pp. 263. ISBN 80-246-0116-8.
Intestinal infections
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