membrane protein and lipopolysaccharide antigen, flagellar protein
Source
warm-blooded animals (poultry, pig)
Transmission
ingestion of contaminated food and water, contact with an infected animal, sexual intercourse
Occurrence
gastrointestinal tract of warm-blooded animals
Incubation time
1-7 days
Disease
campylobacter enteritis
Diagnostics
rectal swab and cultivation on selective soils, latex agglutination (presence of antigens in stool), serology
Therapy
rehydration, macrolides, tetracyclines, chloramphenicol, aminoglycosides (ATB only for more serious infections)
MeSH ID
D002167
Template:Infobox - bakterie
The genus Campylobacter are Gram-negative , thermophilic bacteria adapted to the digestive tract of most warm-blooded animals. It belongs to the family Campylobacteraceae, the order Campylobacterales, the class Epsilon Proteobacteria, the strain Proteobacteria, the domain Bacteria.
The genus includes 18 species , 11 of which have been shown to cause the disease. Pathogenic species are transmissible to humans and cause campylobacter enteritis. The best known members of the genus are C. jejuni, C. coli, C. lari, C. fetus and C. pylori (now known as Helicobacter pylori ).
Bacteria of this genus are spiral or curved non-sporulating rods. If they get in adverse conditions, they can form coco-shaped forms. They have polarly located flagella, which ensure mobility.
Cultivation
Campylobacter needs special conditions for its growth. They grow in a microaerophilic environment, ie. in a low oxygen environment (usually 5% oxygen and 10% carbon dioxide is used for capture) . They require special cultivation soils and sufficient humidity, the optimal temperature is 42-43 ° C . In stool culture, a mixture of antibiotics is added to block the growth of other bacteria present (Skirrow's medium). They form creepingcolonies within 2-7 days .
Due to these growth demands, they were not identified as human pathogens until the end of the 20th century.
Occurence and resistance in the environment
In nature, microbes of the genus Campylobacter are very common, they occur in the intestines of animals (mainly pigs - C. coli , poultry - C. jejuni and C. lari and cattle - C. fetus ) and in birds. They are able to survive longer at refrigerator temperatures (4 ° C) in water, milk, food and faeces; they remain infectious for about 3 weeks. They can be destroyed, for example, by pasteurization, acidic pH or chlorination. They are extremely sensitive to drying and most of the disinfectants used.
Disease
In animal hosts, campylobacters are usually asymptomatic, but can cause abortions in sheep, for example. In humans, pathogenic species cause campylobacteriosis (most commonly C. jejuni ).
BEDNÁŘ, Marek, Andrej SOUČEK and Věra FRAŇKOVÁ, et al. Medical microbiology: Bacteriology, virology, parasitology. 1st edition. Prague: Marvil, 1999. 558 pp. 284-285. ISBN 8023802976 .
↑Jump up to:a b BENEŠ, Jiří, et al. Infectious medicine. 1st edition. Galén, 2009. 651 pp. 242-244. ISBN 978-80-7262-644-1 .
BENEŠ, Jiří. Infectious medicine. 1st edition edition. Galén, 2009. 651 pp. ISBN 978-80-7262-644-1 .
JURAJDA, Vladimir. Poultry and bird diseases: bacterial and fungal infections. 1st edition. Brno: Veterinární a Farmaceutická univerzita, 2003. 185 pp. ISBN 80-7305-464-7 .
BEDNÁŘ, Marek, Andrej SOUČEK and Věra FRAŇKOVÁ, et al. Medical microbiology: Bacteriology, virology, parasitology. 1st edition. Prague: Marvil, 1996. 558 pp. ISBN 8023802976 .
