Morphine intoxication

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Opiates are natural substances from opium (juice from unripe poppies). These are morphine , heroin , codeine , etc. They are substances that stimulate opiate - endorphin receptors in the CNS , have a sedative and analgesic effect.

Overdose[edit | edit source]

Antidota: naloxon, naltrexon

In case of overdose, there is a depression of consciousness, depression of the respiratory center (brachypnea, apnea) in the medulla oblongata and death. The effect of opiates peaks in 2-3 hours after ingestion.

Clinical picture[edit | edit source]

Therapy[edit | edit source]

The antidote is the specific opioid antagonist naloxone (Intrenon®), naltrexone

  • We give it for signs of respiratory depression, even 0.1 mg after 2 minutes to a dose of 2 mg;

in more severe conditions UPV is required , in case of pulmonary edema oxygen and PEEP .


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