Kupffer cells are macrophages, that, together with the endothelium form the lining of the liver sinusoids. Physiologically, they participate in the removal of old or damaged erythrocytes from the blood, this function becomes more important after splenectomy. They are also an important component of innate immunity. Their activation is involved in the initial liver damage in alcoholic steatosis.
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Liver as a histological preparation:
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- LÜLLMANN-RAUCH, Renate. Histology. 1st edition. 2012. ISBN 978-80-247-3729-4.
- MESCHER, Anthony L – JUNQUEIRA, Luiz Carlos Uchôa. Junqueira's Basic Histology. 12th edition. 2009. 480 pp. ISBN 9780071630207.