From WikiLectures

hepatocyte in HE

Hepatocytes make up about 80% of the cells in the liver.

  • are large polyhedral epithelial cells, with large round centrally located nuclei (2 or more)
  • grouped in interconnected plates that are arranged into thousand of small polyhedral lobules
  • store glucose in the form of glycogen , also vitamin B12, folic acid and iron
  • participate in the turnover and transport of lipids.
  • synthesize some of the plasma proteins (albumin, α and β globulins, prothrombin, fibrinogen
  • metabolize/detoxify fat
  • participate in the turnover of steroid hormones.
  • regulates cholesterol level
  • secrete bile (up to 1 liter per day)

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