The term Graaf follicle (vesicular follicle) refers to a mature ovarian follicle in the final stage of development following ovulation. Sometimes, however, this name refers purely to the preovulatory phase, a few hours before ovulation.
It is formed by an oocyte' (about 130 μm in diameter) and surrounding supporting (follicular or granulose) cells. It has a spherical shape, in which there is an enlargement of the cavity (antra), which is filled with a fluid, between the follicular cells. The oocyte is located at the edge of this internal cavity, it is surrounded on all sides by an island of follicular cells - these cells therefore form the so-called cumulus oophorus. Surrounding the oocyte is an amorphous envelope, the zona pellucida.
Related Articles[edit | edit source]
References[edit | edit source]
- JUNQUIERA, L.Carlos – CARNEIRO, Jose – KELLEY, Robert O, et al. Fundamentals of Histology. 1. edition. Jinocany : H & H, 1997. 502 pp. ISBN 80-85787-37-7.
- BENEŠ, George. Study Materials [online]. [cit. 2009]. <http://jirben.wz.cz>.