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Ceruloplazmin is a plasma protein produced in liver, which can revesibly bind 6 atoms of copper in it's molecule. Defect of this form of copper transport by ceruloplasmin causes Wilson's desease. Another function of ceruloplasmin is prevention of forming dangerous hydroxyl radicals, in so called Fenton's reaction by catalizing oxidation of Fe2+ to Fe3+.[1] Ceruloplasmin is a significant acute phase reactants. It's blood concentration physiologically rises in pregnancy.

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  1. RACEK, J, et al. Klinická biochemie. První vydání. Praha : Galén – Karolinum, 1999. s. 63. ISBN 80-7262-023-1.

Kategorie:Biochemie Kategorie:Fyziologie