It is a topical polypeptide antibiotics, the mechanism of action of which lies in the inhibition of the formation of the bacterial wall. When applied topically, it is excellently tolerated. A small incidence of resistance is observed.
Spectrum[edit | edit source]
Includes gram positive cocci and rods.
Indication[edit | edit source]
In combination with neomycin sulphate, it forms Framycoin, of which it adds a gram-positive spectrum (neomycin acts on gram-negative microbes and staphylococci).
Side effects[edit | edit source]
They are similar to neomycin (mainly nephrotoxicity). Systemic absorption is undesirable.
Links[edit | edit source]
Related articles[edit | edit source]
Bibliography[edit | edit source]
- FARGHALI, Dagmar, et al. Základní a aplikovaná farmakologie. 2. edition. Praha : Galén, 2007. ISBN 978-80-7262-373-0.