From WikiLectures


Bacitracin ointment
chemical structure of Bacitracin

It is a topical polypeptide antibiotics, the mechanism of action of which lies in the inhibition of the formation of the bacterial wall. When applied topically, it is excellently tolerated. A small incidence of resistance is observed.

Spectrum[edit | edit source]

Includes gram positive cocci and rods.

Indication[edit | edit source]

In combination with neomycin sulphate, it forms Framycoin, of which it adds a gram-positive spectrum (neomycin acts on gram-negative microbes and staphylococci).

Side effects[edit | edit source]

They are similar to neomycin (mainly nephrotoxicity). Systemic absorption is undesirable.

Links[edit | edit source]

Related articles[edit | edit source]

Bibliography[edit | edit source]

  • FARGHALI, Dagmar, et al. Základní a aplikovaná farmakologie. 2. edition. Praha : Galén, 2007. ISBN 978-80-7262-373-0.

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