Tumors of peripheral nerves

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Schwannoma on MRI

Peripheral nerve tumors can arise from Schwann cells, fibroblasts or perineural cells.

Among the most important representatives are "neurinoma (schwannoma, neurilema)", neurofibroma, tumor of granular cells, as well as perineurioma, neurothecoma or malignant peripheral nerve sheath tumor (MPNST - malignant peripheral nerve sheath tumor).

Schwannoma[edit | edit source]

  • In neurofibromatosis, these are usually multiple, chain-like tumors of various sizes on many nerves.
  • The tumor usually destroys the fascicle from which it originates, the other fascicles follow the tumor and are stretched and compressed.
  • They are also of considerable size.
  • Therapy: the tumor has a capsule, the functional fascicles are usually easily separated from the capsule and only the tumor is removed.
  • Paresis may improve over time.
  • In the histological image, two variants of the tumor are visible, referred to as Antoni variant A and B. Type A is characterized by its staggered nuclei, such an arrangement is referred to as Verocay bodies. Type B shows a more myxoid character, it does not contain stapling of the nuclei. Both variants can be found in the same tumor.

Links[edit | edit source]

Related Articles[edit | edit source]

Source[edit | edit source]

    • BENEŠ, Jiří. Studijní materiály [online]. ©2007. [cit. 2010]. <http://www.jirben.wz.cz/>.

References[edit | edit source]

    • ZEMAN, Miroslav, et al. Speciální chirurgie. 2. vydání. Praha : Galén, 2004. 575 s. ISBN 80-7262-260-9.
    • POVÝŠIL, Ctibor, et al. Obecná patologie. 1. vydání. Praha : Galén, 2011. 290 s. ISBN 978-80-7262-773-8.