From WikiLectures


Detachment of the necrotic tissue from the viable tissue around it. It can also reffer to a situation in which a portion of a blood or tissue liquid becomes stationary without partaking in blood circulation. Sequestration = separation of a part from the whole:

  1. The process of sequester formation
  2. The process in which a portion of blood/tissue liquid grow separated from the circulation.
    • Symptoms and consequences for the blood circulation are very similar to signs of blood loss or dehydration. (As it happens for instance when intestinal liquid gets sequestrated due to its obstruction (ileus)).

Sequester is the name for the part that has been separated from the whole. Usually, it is a part of a necrotic tissue (most often bone tissue) that becomes separated from the surrounding viable tissue (lat. Sequestro = to divide).



  • VOKURKA, Martin – HUGO, Jan. Velký lékařský slovník. 8. edition. Praha : Maxdorf, 2009. 1144 pp. ISBN 978-80-7345-166-0.