Manganese


Manganese is important for bone structure, CNS function and a whole range of enzymes (pyruvate carboxylases, SOD, kinases, decarboxylases...).

Manganese v PSP

Function

It participates in the process of oxidative phosphorylation , thereby interfering with fat metabolism → highest concentration in cells – in mitochondria.

Source

Sources of manganese are oatmeal, whole grain bread, tea and cocoa. The estimated daily requirement (recommended dose cannot be determined) is 2-3 mg[1]. It is excreted in bile

Deficit

The deficiency is exceptional, it can cause an increase in the level of blood lipids and associated premature atherosclerosis. Dermatitis or digestive disorders can also occur.

Toxicity

In the 19th century, it manifested itself in miners - "manganese madness" - mental disorders, parkinsonism.

References

  1. BENCKO, Vladimír, et al. Hygiena – učební texty k seminářům a praktickým cvičením. 2. edition. Prague : Charles University, 2002. 204 pp. ISBN 80-7184-551-5.

Source


References

  • BENCKO, Vladimír, et al. Hygiena - učební texty k seminářům a praktickým cvičením. 2. edition. Prague : Charles University, 2002. 204 pp. ISBN 80-7184-551-5.
  • SCHNEIDERKA, Petr, et al. Kapitoly z klinické biochemie. 2. edition. Prague : Karolinum, 2004. ISBN 80-246-0678-X.
  • MASOPUST, Jaroslav – PRŮŠA, Richard, et al. Patobiochemie metabolických drah. 2. edition. Prague : Charles University, 2004. 192; 208 pp.