Krabbe disease

From WikiLectures

Multinucleated macrophages with PAS-positive inclusions, so-called globoid cells

Krabbe disease (also Krabbe globoid leukodystrophy ) is a leukodystrophy . It is one of the inherited diseases caused by a congenital defect of lysosomal enzymes. The result is an unrestricted, non-tumor accumulation of mature adipose tissue in places where it does not normally occur. This is a galactocerebroside β-galactosidase deficiency. It affects CNS cells.

Links[edit | edit source]

related articles[edit | edit source]

Source[edit | edit source]

    • VOKURKA, Martin and Jan HUGO, et al. Great Medical Dictionary [online]  . 8th edition. Prague: Maxdorf, 2009. 1144 pp. Also available from < >. 
Screen Shot 2022-02-22 at 3.02.12 PM.png