Ischemic heart disease/repetitorium

Atherosclerosis

Myocardial blood supply disorders

Important terms: anatomy of the coronary arteries, regulation of blood flow.

Causes

1. Increasing coronary artery resistance
   • Functional: vasoconstriction

   shortening of diastole

   • Anatomical: thickening of the vessel wall (atherosclerosis)

   thrombi, emboli

   • Combination of both
2. Decrease in driving pressure: drop in (diastolic) BP in the aorta

   increase in right atrial pressure

• Vasodilator treatment – stealing phenomenon
• Invasive treatment

Ischemic heart disease (IHD)

• Causes: Limited blood flow in coronary vessels
• Consequences of ischemia: impaired contractility, arrhythmia, angina pectoris, necrosis
• Manifestations of myocardial ischemia on EKG
• Biochemical manifestations of ischemia

Symptoms

1. Angina pectoris'
   • Stable
   • Unstable
   • Prinzmetal's
2. Heart-attack
   • Subjective symptoms
   • ECG: T inversion, ST elevation, deep Q
   • Biochemical tests in acute myocardial infarction
   • Possibly sudden death

• Principles of treatment and prevention

Links

Related Articles

• Heart
• Ischemic heart disease
• Heart-attack
• ECG

Source

• VIZEK, Martin. Repetitorium [online]. [cit. 2011-11-11]. <https://web.archive.org/web/20130512032641/http://pf.lf2.cuni.cz/vyuka/repetitorium.html>.