From WikiLectures

They belong to RNA viruses, in the genus Aphtovirus and contain 33 different serotypes.

Disease[edit | edit source]

Most diseases will have severe consequences.

Pathogenesis[edit | edit source]

  • gate of entry: mainly through food, exceptionally through the respiratory system
  • multiplication in cells
  • hematogenous spread
  • the clinical consequences depend on the place of attachment of the virus and on the individual sensitivity of the individual.
  • the virus is intensively secreted from the infected mucosa.

Diagnostics[edit | edit source]

  • incubation from nasopharyngeal swabs, from stool, or from cerebrospinal fluid on cell cultures from monkey kidneys, or on mice.
  • serological diagnosis using a neutralization test.

Epidemiology[edit | edit source]

The source of the virus is an infected person, who is already infectious at the end of the incubation period (3 to 7 days). The disease occurs mainly in summer and early autumn.

Links[edit | edit source]

References[edit | edit source]

  • JIŘÍ, Horáček. Základy lékařské mikrobiologie. 1. edition. Praha : Karolinum, 2000. 309 pp. vol. 1. ISBN 80-246-0006-4.