It is a type of amyloidosis, which is mainly associated with long-term hemodialysis patients. It occurs because of accumulated β2-microglobulin protein, which cannot be excreted by damaged kidneys. Constantly increased plasma concentration is required for amyloid formation. β2-microglobulin has a high affinity for collagen therefore amyloid fibrils are formed primarily in bones, joints, periarticular tissues, and tendons (carpal tunnel syndrome).
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- SULKOVÁ, Sylvie. Hemodialýza. 1. edition. MAXDORF, 2000. pp. 693. ISBN 80-85912-22-8.