Chronic bronchitis

From WikiLectures

Chronic bronchitis is defined as a chronic productive cough lasting at least three months in two consecutive years, and at the same time, other possible causes of cough - pulmonary ( bronchiectasis ) and non-pulmonary ( heart failure ) are excluded. The disease is further characterized by an obstructive ventilation disorder.

Chronic bronchitis:

Chronic bronchitis 2:

Chronic bronchitis can be considered a component of chronic obstructive pulmonary disease (the other component being emphysema ).

Etiology[edit | edit source]

  • Endogenous causes
  1. age (incidence increases with age) and male gender (men are affected twice as often as women),
  2. individual predisposition – atopy, immune disorders,
  3. sinusitis (sinobronchial syndrome),
  • exogenous causes
  1. smoking – represents probably the most significant risk factor,
  2. repeated respiratory infections – mainly haemophilic and pneumococcal,
  3. work and environmental pollution.

Pathology[edit | edit source]

Inflammatory infiltration of the wall of the bronchi, at the same time there are increased and hypertrophic mucus glands in the mucosa (overproduction of mucus). These changes lead to a narrowing of the lumen of the bronchi and thus to an obstructive air flow disorder.

Definition, pathogenesis, symptoms, complications, treatment

Manifestations of the disease[edit | edit source]

Spirometric examination – obstructive pulmonary ventilation disorder

Disease types[edit | edit source]

  1. Simple chronic bronchitis
  2. Purulent chronic bronchitis
  3. Obstructive chronic bronchitis
Spirometric examination – obstructive pulmonary ventilation disorder
Spirometric examination – obstructive pulmonary ventilation disorder

Investigation[edit | edit source]

  • Medical history (smoker, work environment, recurrent DCD infection),
  • physical examination - may be completely without findings,
  • X-ray of the lungs – to rule out infection, bronchogenic carcinoma,
  • spirometric examination – reveals an obstructive lung ventilation disorder,
  • bronchoscopy - in cases of uncertainty, suspicion of bronchogenic carcinoma .

Therapy[edit | edit source]

The therapy of chronic bronchitis is similar to the therapy of COPD, it involves the administration of inhaled forms of drugs, often in combination.

  • Inhaled corticosteroids (ICS),
  • inhalation bronchodilators ,
    • β 2 agonist (THIRD, SEVEN),
    • anticholinergic (SAME, OLD).

Quitting smoking is an integral part of the therapy .

Links[edit | edit source]

Related Articles[edit | edit source]

References[edit | edit source]

  • KLENER, Pavel, et al. Vnitřní lékařství. 3. edition. Praha : Galén, 2006. 285 - 286 pp. ISBN 80-7262-430-X.