Biosynthesis of glycoproteins and their importance .
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Glycopeptides are highly effective bactericidal antibiotika.
Mechanism of action[edit | edit source]
They inhibit cell wall synthesis bakterií.
Antimicrobial spectrum[edit | edit source]
They are only effective against G+, especially staphylococci resistant to meticilinu (oxacilinu), further enterococci, Streptococcus pneumoniae, Streptococcus pyogenes, Clostridium difficile.
The two main antibiotics are vancomycin and teicoplanin.
Vancomycin[edit | edit source]
náhled|Vankomycin __Vankomycin
Teicoplanin[edit | edit source]
Teicoplanin is a glycopeptide with a spectrum similar to vancomycin. It has no cross-resistance with it, is very well tolerated and non-toxic. It is intended for parenteral administration. It has a longer biological half-life than vancomycin.
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Source[edit | edit source]
Použitá literatura[edit | edit source]
Kategorie:Farmakologie Kategorie:Infekční lékařství Kategorie:Mikrobiologie
