Bacterial vaginosis

From WikiLectures

Gardnerella vaginalis in a vaginal swab

Bacterial vaginosis is a polymicrobial clinical syndrome characterized by a partial reduction or disappearance of lactobacilli and, conversely, an overgrowth of aerobic and anaerobic bacteria in the vagina.[1] These are bacteria that are commonly found here (Gardnerella vaginalis, Prevotella, Mobiluncus). It is a non-inflammatory disease and is the most common cause of vaginal fluorosis (discharge) in sexually active women.

Clinical presentation[edit | edit source]

It is manifested by a grey-white vaginal discharge with a characteristic "fishy smell". This may appear only after the addition of 10% KOH.

Diagnosis[edit | edit source]

If suspected, measure vaginal fluoride pH, which is > 4.5. In the native microscopic specimen, we find numerous epithelial cells and a granular appearance of the cytoplasm for the presence of a large number of bacteria.

Differential diagnosis[edit | edit source]

We distinguish bacterial vaginosis from vaginitis.

Iron

Therapy[edit | edit source]

Metronidazole 2 × 500 mg/day for 7 days, or metronidazole gel for 5 days, or clindamycin 2% cream for 7 days.

Course and prognosis[edit | edit source]

Vaginosis left untreated increases the risk of sexually transmitted infections, premature amniotic fluid drainage and childbirth.


Links[edit | edit source]

Related articles[edit | edit source]

References[edit | edit source]

  1. ROB, Lukáš – MARTAN, Alois – CITTERBART, Karel, et al. Gynekologie. 2. edition. Praha : Galén, 2008. 343 pp. pp. 134. ISBN 978-80-7262-501-7.

Bibliography[edit | edit source]

  • ŠTORK, Jiří, et al. Dermatovenerologie. 1. edition. Praha : Galén, Karolinum, 2008. 502 pp. ISBN 978-80-7262-371-6.