Böök syndrome

From WikiLectures

Synonyms: PHC syndrome, aplasia of premolars, hyperhidrosis.

Named after the Swedish geneticist Jan Böök who first described the disease in 1950.[1]



  • premature greying,
  • palmar and plantar hyperkeratosis,
  • hypodontia,
  • aplasia of premolars.

Links[edit | edit source]

Reference[edit | edit source]

  1. a b BOOK, J A. Clinical and genetical studies of hypodontia. I. Premolar aplasia, hyperhidrosis, and canities prematura; a new hereditary syndrome in man. Am J Hum Genet [online]1950, y. 3, p. 240-63, Available from <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1716355/?tool=pubmed>. ISSN 0002-9297. 

References[edit | edit source]

  • LAZOVSKIS, Ilmars – DOBIÁŠ, Václav. Overview of clinical symptoms and syndromes. 2. edition. Avicenum, zdravotnické nakladatelství, 1990. 0 pp. ISBN 80-201-0043-1.