A palindrome

From WikiLectures

Example of palindromic DNA sequence (blue) and cleavage of sticky ends (red)

A palindrome (or palindromic sequence) is a short sequence of nucleotides' in the chain DNA that reads the same whether from 3 ', or 5' ends.

These sequences are cleaved with the help of bacterial endonucleases, which prevents bacteria from the penetration of foreign nucleic acid. This property of restriction enzymes is used in the ``nucleic acid analysis methods. Inverted repeats can sometimes be confused with the name palindrome. However, this designation is inaccurate, because it is a sequence of nucleotides complementary to another sequence, but it has a difference in the order of the bases, which are reversed according to the mirror.

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  • KOHOUTOVÁ, Milada, et al. Medical biology and genetics. (Part II). 1. edition. Prague : Karolinum, 2012. 202 pp. ISBN 978-80-246-1873-9.