Folic acid also is known as vitamin B9, folate or folacin . Includes a group of compounds: Folic Acid (contains pterin, p-aminobenzoic acid and glutamic ) and folic acid. Along with vitamin B12 is essential for the formation of nucleic acids and thus for synthesis of DNA , participate in the transfer radicals and in all processes of cell division , it is important for cell division and tissue with high mitotic activity.Absorbed in the proximal parts of the small intestine and when excess it is excreted in the urine.
Source[✎ edit | edit source]
Liver, yeast, green leafy vegetables, as well as whole grain cereals, meat, milk, eggs and legumes. The recommended daily adult dose: 400mg. In pregnancy, 600mg for prevention of congenital malformations (mainly cleft neural tube).
Deficit[✎ edit | edit source]
Deficiency of vitamin B9 occurs in low supply, absorption or increased need during pregnancy. There is a megaloblastic anaemia , which is characterized by the presence of abnormal precursors of red blood cells in the bone marrow. Compared with normal cells are cells arising from these abnormal precursors of different shape, larger size, reduced viability and reduced ability to transport oxygen . Along with the lack of iron is its lack of a significant cause of anaemia in developing countries. Deficiency during pregnancy causes spina neural tube in the fetus.
- Laboratory evaluation: serum levels of folate, total homocysteine (increases in the absence, also in the absence of vitamin B12)
Surplus[✎ edit | edit source]
High intake of folic acid can mask vitamin B12 , so the upper limit of the daily recommended intake of up to 1000 mg / day.
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Related articles[✎ edit | edit source]
Bibliography[✎ edit | edit source]
- BENCKO, Vladimir, et al. Hygiene and epidemiology : selected chapters. 2. edition. Prague. 2008. ISBN 80-246-0793-X.