Types of Metaphase Chromosomes

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Chromosome Characteristics
Metacentric Centromere lies roughly in the middle of the chromosome.
Submetacentric The centromere is positioned in such a way that p bundle branch structure are significantly shorter than bundle branch q.
Acrocentric The centromere is shifted to one end of the chromosome; The P arm is very short.
Telocentric The centromere lies at the end of the chromosome; The chromosome has only Q bundle arms (not found in humans).
Holocentric Formations performing the function of a centromere are scattered along the entire length of the chromosome (not found in humans, rarely occurs e.g. in Caenorhabditis elegans).

For an accurate distinction between metacentric, submetacentric, and possibly acrocentric chromosomes, the value of centromeric index is crucial[1].

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  1. KOČÁREK, Eduard – PÁNEK, Martin – NOVOTNÁ, Drahuše. Klinická cytogenetika I.: úvod do klinické cytogenetiky, vyšetřovací metody v klinické cytogenetice. 1.. edition. Karolinum, 2006. 120 pp. ISBN 80-246-1069-8.