Thyrotoxic crisis

The thyrotoxic crisis occurs by exacerbating the symptoms of hyperthyroidism to such an extent that it threatens the patient's life.

Clinical manifestations

• significant tachycardia (up to 150/min)
• Unrest, tremor, higher temperature
• Abdominal pain, nausea, vomiting, diarrhea, dehydration
• delirious states

Etiopathogenesis

• A thyrotoxic crisis can be caused by untreated or poor treatment of hyperthyroidism, which is associated with infection, surgery or injury.
• Discontinuation of established thyrostatic therapy.
• It can also be caused by iodine preparations.

Diagnostics

Laboratory elevation of thyroid hormones (T3, T4).

Treatment

• Administration of thyrostatics (carbimazole p.o. or NGT), eventually Lugol's solution.
• beta-blockers for the treatment of cardiovascular problems.
• Glucocorticoids, the administration of which prevents heart failure.
• Physical cooling or paracetamol to reduce the temperature.
• Correction of dehydration of the organism, oxygen therapy.
• Preventive ATB and reassuring the patient.
• Benzodiazepines
• After unsuccessful exhaustion of all treatment, we proceed to plasmapheresis and peritoneal dialysis.