Simultaneous combined immunization

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It is performed as prophylaxis after exposure. It is possible to submit at the same time:

inactivated or subunit vaccines together with immunoglobulins – there is a slight reduction in the level of antibodies produced. This combination is used in post-exposure prophylaxis (good protection against infection is achieved in an exposed person).
live vaccines together with immunoglobulins – the combination is usually unsuccessful, as there will be a significant reduction in the level of antibodies produced. Vaccination is therefore carried out min. 3-5 months after immunoglobulin administration, or immunoglobulins are administered 3-8 weeks after vaccination. An exception is the polio vaccine, yellow fever and typhoid, which elicit an immune response that does not interfere with antibodies delivered by passive immunization.^[1]

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