Serine

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Serine molecule

Serine is one of the non-essential amino acids. Under the term non-essential we understand that the human body is able to create it itself, so there is no need for food intake.

It can be converted to glycine by the enzyme serine hydroxymethyltransferase. In the human body, it is synthesized from 3-phosphoglycerate. It is a precursor of the amino acid selenocysteine. Decarboxylation of serine produces ethanolamine, which by triple methylation forms choline, a precursor of acetylcholine, which is a very important neuromodulator.


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  • MATOUŠ, Bohuslav. Základy lékařské chemie a biochemie. 2010. edition. Prague : Galén, 2010. 540 pp. ISBN 978-80-7262-702-8.