náhled|200px|Nespolupráce pacienta („non-compliance“) Refractory hypertension (synonym Resistant hypertension, RH) is defined as blood pressure exceeding 140/90 mmHg – despite long enough treatment with triple combinations of antihypertensives of different classes, one of which is a diuretic.
*Currently, the definitions of refractory and resistant hypertension are different: resistant hypertension resists combination therapy of three groups of antihypertensives, one of which is a diuretic, while refractory hypertension resists combination of even five different groups of antihypertensives.
Risks[edit | edit source]
Patients with refractory hypertension have a higher risk of (compared to compensated hypertension):
Causes[edit | edit source]
The causes of refractory hypertension include:
- secondary hypertension (must be treated causally);
- inadequate antihypertensive treatment (inappropriate combination of antihypertensive drugs, inappropriate dosage);
- associated diseases;
- concomitant use of nonsteroidal antirheumatic drugs;
- patient non-cooperation (patient does not respect the recommended doses and / or intervals; refuses to influence an unhealthy lifestyle: smoking, alcohol, salt, physical activity).
Links[edit | edit source]
Resources[edit | edit source]
- HOLAJ, Robert. Kardiologický kroužek. III. interní klinika VFN a 1. LF UK v Praze, 2009.