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Prothrombin is an inactive form of coagulation factor II. It is produced by the liver and its formation is dependent on the presence of vitamin K. Using a complex of substances known as prothrombin activator, prothrombin is activated to thrombin.

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ŠVÍGLEROVÁ, Jitka. Protrombin [online]. Poslední revize 18. 2. 2009, [cit. 12.11.2010]. <>