Prostatic Specific Antigen
Prostatic specific antigene is kalikrein-like serotonine protease. It is organ specific tumor marker for prostatic cancer, is produced by secretory epithelial cells .
Normal Value
Normal value is < 4 ng/ml, but with exceptions(!), this value changes with age of man.
| AGE | MEDIAN (ng/ml) | Limit value (ng/ml) |
|---|---|---|
| 40–49 | 0,7 | 2,5 |
| 50–59 | 0,9 | 3,5 |
| 60–69 | 1,4 | 4,5 |
| >70 | 1,4 | 6,5 |
The value of PSA can be artificially elevated by prostatitis (infection), bicycling, ejaculation, instrumental examination of male urethra or examination of prostate by DRE.[1]
Possible Characteristics of PSA
- free/total PSA
- PSAD (density) = PSA/body weight
- PSAV (velocity) = increase per 1 year
- PSADT (doubling time)
Links
Related Articles
Bibliography
- DVOŘÁČEK, Jan. Karcinom prostaty [lecture for subject Urology, specialization Generral Medicine, 1. LF UK Charles University in Prague]. Prague. 2012.
References
- ↑ HANUŠ, Tomáš. Urologie. 1. edition. Prague : Triton, 2011. pp. 133. ISBN 978-80-7387-387-5.
