Pressure amplitude

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Pressure amplitude (also pulse or pulse pressure) is the difference between systolic and diastolic pressure . At physiological blood pressure values (120/80 mmHg), the pressure amplitude is 40 mmHg. The pressure amplitude is highest in the large arteries, decreasing towards the periphery. The magnitude of the pressure amplitude mainly determines the systolic volume and the compliance of the vessels. An increase in systolic volume (eg during muscle work) leads to an increase in pressure amplitude, while greater vascular compliance reduces the pressure amplitude.