Mirtazapine
From WikiLectures
Mirtazapine is an antidepressant, that blocks α2-receptors on the presynaptic membrane of neurons in the CNS. This increases the release of noradrenalin and serotonin, which has a positive effect in depression therapy after one to two weeks. It belongs to the group of antidepressants with a dual effect, the so-called NaSSA (Noradrenergic and Specific Serotonergic Antidepressant). The usual dose is 15–45 mg once a day.
Typical side effects for mirtazapine include increased appetite, sedation and dry mouth. On the contrary, compared to antidepressants of the type SSRI and SNRI, sexual dysfunction occurs less often.
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Literature used[edit | edit source]
- the Czech Republic. SÚKL. Souhrn údajů o přípravku. 2020. Available from <https://www.sukl.cz/modules/medication/download.php?file=SPC163346.pdf&type=spc&as=esprital-spc>.
- RACKOVÁ, Sylva. Využití mirtazapinu v klinické praxi. Psychiatrie pro praxi [online]. 2017, vol. 18, p. 64–68, Available from <https://www.psychiatriepropraxi.cz/pdfs/psy/2017/02/04.pdf>. ISSN 1803-5272.
