Mikulicz syndrome

From WikiLectures

Mikulicz syndrome is a rare, painless bilateral swelling of the lacrimal, parotid, and submandibular glands, which, however, may not lead to a clinically manifest dysfunction, especially in the salivary glands. Patients are usually older, women are more often affected. Historically, Mikulicz syndrome was considered a variant of Sjögren's syndrome, now it is considered an organ-specific manifestation of IgG4-associated disease. Mikulicz syndrome is associated with a number of diseases, especially leukemia, lymphoma, and sarcoidosis.

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  • YAMAMOTO, M. – TAKAHASHI, H. – SUGAI, S.. , et al. Clinical and pathological characteristics of Mikulicz's disease (IgG4-related plasmacytic exocrinopathy). Autoimmun Rev. 2005, vol. 4, no. 4, p. 195-200, ISSN 1568-9972. DOI: 10.1016/j.autrev.2004.10.005.