Mental disorders caused by opioids use

From WikiLectures

Why are they taking it?[edit | edit source]

  • used for their euphoric effect
  • high addiction rate

Route of administration:[edit | edit source]

  • IV or inhaled or snorted

Mechanism of Action:[edit | edit source]

  • kappa, delta and mu-receptor agonists
  • Opioid induced disorder → depressive disorder, anxiety disorder, sleep disorder, sexual dysfunction, delirium

Therapy:[edit | edit source]

  • longer-acting opioid e.g. methadone, buprenorphine
  • many internal comorbidities: malnutrition, infections (HIV, HCV), endocarditis, sepsis