Histology MCQs/Mock Credit Test D

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Ernest Board: Leeuwenhoek with his microscope (1912).

Mock credit test. Only one answer is correct.


1 The specimen was processed for staining with Sudan Red dye. Which step of common processing has been skipped?

Necropsy
Chemical fixation
Paraffine embedding
Microtome slicing

2 Mutation of a gene for protein associated with microtubules often leads to respiratory diseases and male infertility due to immobility of spermatozoa. What protein is damaged?

Actin
Myosin
Bombesin
Dynein

3 Which organelle is a site for production of rRNA?

Nucleus
Nucleolus
Ribosome
Smooth endoplasmic reticulum

4 Intermediate filaments are involved in the structure of a nuclear envelope. How are called proteins of these intermediate filaments?

Lamins
Integrins
Nucleons
Pericytes

5 Which cellular structure is main site of glycosylation (O-glycosylation) of proteins?

Rough endoplasmic reticulum
Smooth endoplasmic reticulum
Golgi apparatus
Secretory granules

6 What is main function of zonula occludens (tight junction)?

Mechanical cohesion
Electrical coupling of cells
Chemoreception
Limitation of paracelular transportation

7 Which day after ovulation does implantation usually start?

3rd day
6th day
9th day
12th day

8 Which embryonic structure gives rise an extraembryonic mesoderm?

Hypoblast
Epiblast
Allanthois
Yolk sack

9 Where does the primitive node (node of Hensen) take place?

In the cranial part of the epiblast
In the cranial part of the hypoblast
In the caudal part of the epiblast
In the caudal part of the hypoblast

10 Which structures are connected by canalis neurentericus?

Allanthois and yolk sack
Yolk sack and amnionic cavity
Amnionic cavity and extraembryonic coelom
Extraembryonic coelom and intervillous spaces

11 Which of the following molecules has the main contribution to the differentiation and development of the cranial part of the embryo?

Cerberus
Nodal
BMP4
FGF8

12 What is the embryonic origin of melanocytes?

Epiblast
Hypoblast
Neural tube
Neural crest

13 A part of an embryo develops temporary structures called somites. Which part is it?

Lateral mesoderm
Paraaxial mesoderm
Primitive streak
Neural tube

14 Which embryonic structure does give rise to a nephrogenic blastema?

Intermediary mesoderm
Lateral mesoderm
Neural crest
Extraembryonic mesoderm

15 Which protein is probably the main protein of cytoskeletal filaments associated with hemidesmosomes of enterocytes?

Vimentin
Desmin
Cytokeratin
Actin

16 Epithelial cells with well-developed basal labyrinth have pronounced one function. Which one?

Proteosynthesis
Synthesis of lipids
Resorption of saccharides
Transportation of ions

17 Which staining is proving that the specimen of a planar epithelium contains goblet cells?

Alcian blue
Preussian blue
Anilin blue
Luxol blue

18 Two samples of liver have been harvested from a healthy volunteer briefly after food and after a period of fasting. The first sample contains plenty of PAS-positive granules, whereas the second sample contains few of them only. From which material are those granules composed?

Fat
Mucus
Glucose
Glycogen

19 Let us take the same situation as in the previous question- liver with granules of glycogen. Sometimes, especially under pathological conditions, the liver can contain PAS-positive granules composed of material other than glycogen. How to prove that the granules are really composed of glycogen?

Confocal microscope
Enzyme immunohistochemistry
Feulgen reaction
Diastaze reaction

20 In an adult human body, only one organ contains reticular epithelium. Which one?

Thymus
Spleem
Bone marrow
Dental pulp

21 Plasma cells have several morphological hallmarks. One of them is a juxtanuclear clearing (site of lower stainability of cytoplasm close to the nucleus) on histological specimens. Which organelle takes place in the site of the juxtanuclear clearing?

Smooth endoplasmic reticulum
Rough endoplasmic reticulum
Golgi apparatus
Lysosomes

22 Imagine the function of a fibroblast and decide the question about the stainability of its cytoplasm in basic staining techniques.

Basophilic
Acidophilic
Neutrophilic
Amphiphilic

23 Which part of a cell does produce hyaluronic acid?

Rough endoplasmic reticulum
Golgi apparatus
Lysosomes
Cell membrane

24 Jelly-like connective tissue is an uncommon type of tissue. Where can one find it?

Lamina propria of tongue
Umbilical cord
Lamina propria of small intestine
Subcutaneous tissue in periorbital region

25 Which type of collagen is the main protein of the fibrillary component of the ECM of primary bone?

Type I collagen
Type II collagen
Type III collagen
There is no collagen in primary bone

26 How many dendrites has a bipolar neuron?

0
1
2
it depends on a subtype of neuron

27 Histological specimens of peripheral nerves of a patient with a certain disease show dropouts of stainability by Luxol Blue. What will be the most pronounced clinical manifestation?

Severe spasms
Strong pain
Muscle weakness
There will be probably no issue

28 Imagine the red lineage of hematopoiesis. Which stage of the lineage precedes the stage of polychromatophilic erythroblast?

proerythroblast
basophilic erythroblast
ortochromatophilic erythroblast
reticulocyy

29 Pronounced muscle stiffness called rigor mortis develops within several hours after death. The strength of the contraction is in the intensity comparable with maximal voluntary contraction. Use your knowledge and choose the most plausible hypothesis about the mechanism behind rigor mortis.

Agonal anaerobic metabolism overproduces lactate. Subsequent acidity denatures actin filaments.
Terminally, calcium is released from mitochondria. Calcium forms stiff complexes with proteins.
Consumption of ATP prevents dissociation of actin from myosin.
A drop in activity of ion pumps causes intracellular swelling and subsequent stiffness.

30 From the perspective of a secretory cell, holocrine secretion is similar to one of the following historical events. Which one?

Reconstruction of the Battle of Vítkov (1920/1420), during which the Hussites were mistakenly defeated by Crusaders.
Battle of Königgrätz (1866), during which Prussians achieved the overwhelming victory due to having Dreyse's breechloading needle guns and mainly due to the tactical inferiority of the Austrian army.
Battle of Aspern (1809), in which the archduke Karl Ludwig caused the first big defeat to the emperor Napoleon Bonaparte.
Battle of Hastings (1066), which was followed by a massacre of soldiers of Harold Godwinson, the last Anglo-Saxon king of England.


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