Histology MCQs/Epithelial Tissue (2026/27)

1

Which type of collagen takes place inside the basement membrane of epithelia?

type I collagen
type II collagen
type III collagen
type IV collagen

2

Which type if intermediate filaments is a hallmark of epithelial cells?

keratins
vimentin
desmin
GFAP

3

What is main shape of cells in the intermediary layer of planar epithelia?

columnar
polygonal
kuboid
squamous

4

Which type of epithelia is adapted to facing a chemically aggresive environment?

pseudostratified columnar epithelium
stratified squamous non-keratinizing epithelium
simple columnar epithelium
trabecular epithelium

5

Epithelium lining striated ducts of big salivary glands has well-developed balas labyrinth. Which function is performed by the structure?

tuning of ionic composition of the saliva
secretion of antibodies to the saliva
reabsorption of glucose from the saliva
sensing of pH of the produced saliva

6

Hepatocytes (epithelial cells of liver) in the periportal area are more basophilic. Which function is connected with the basophilicity?

storage of glucose in the glycogen
endocrine secretion of proteins
exocrine secretion of proteins
storage of vitamin A

7

Which type of cytoskeleton is responsible for maintaining the shape of the unit of the brush border on the apical pole of, e.g., enterocytes?

microtubules
actin filaments
vimentin filaments
fibrils of type II collagen

8

Polarity of epithelial cells is maintained by the action of one type of cell adhesion, despite the main function of the cell adhesion is to prevent paracellular transportation. Which cell addhesion is it?

adherent junction
tight junction
gap junction
desmosome

9

Which motor protein ensures the beating of cillia in pseudostratified cilliated columnar epithelium?

kinesin
myosin
dynein
aktin

10

The picture is a schematic drawing of germinal epithelium in the seminiferous tubule in testis. Sertoli cells (7) are surrounded by sperms in different developmental stages. Which morphological type describes the shape of Sertoli cells the best?

trabecular epithelium
simple columnar epithelium
stratified columnar epithelium
pseudostratified columnar epithelium

11

Reticular epithelium is uncommon. In the adult body, it occur in one organ only. Which one?

bone marrow
lymph none
thymus
spleen

12

Goblet cells are columnar epithelial cells occuring esp. in the respiratory passages and in the intestine. Their function is mainly production of mucus. There is no one mucus, mucus in the respiratory passages is based on mucin 5AC, mucus in the intestine is based on mucin 2. Which method can distinguish respiratory and intestinal goblet cells?

immunohistochemistry
silver impregnation
PAS reaction
alcian blue

13

Squamous (squamocellular) carcinoma is a malignant cancer of epidermis. During the diagnostic procedure, proof of intermediate filaments related to keratinocytes (epithelial cells of epidermis) may be helpful. Which type of intermediate filaments should be detected?

keratins 5 and 6
vimentin
desmin
GFAP

14

Parakeratosis is a pathological remodelation of stratified squamous keratinizing epithelium. The hallmark of parakeratosis is an incomplete maturation of keratinized layer. The most striking morphological feature is that one organelle remains even in the keratinized layer. Which organele is it?

desmosome
cell nucleum
hemidesmosome
keratin filaments

15

Simple cuboidal epithelium of a proximal tubule of kidney reabsorbs (a.o.) glucose from the newly formed urine. If the concentration is high, glucose can be stored in those cells as granules of glycogen in the basal part of the cell. Presence of huge amount of glycogen in those cells is called Armani Ebstain laesion. How to prove that those granules are composed of glycogen?

PAS reaction
Feulgen reaction
Sudan III staining
alcian blue staining