Histology MCQs/Cartilage and Bone (2026/27)

1

How is cartilage supplied with nutrients from the blood?

an a. nutritia enters the cartilage and branches into a rich capillary network
an a. nutritia enters the cartilage and branches into a sparse capillary network
capillaries branching from arterioles of the perichondrium enter the cartilage
cartilage is avascular and is supplied by diffusion from the perichondrium

2

What is the name of the proteoglycan that forms the basis of a large molecular complex responsible for the mechanical properties of cartilage?

aggrecan
hyalectan
perlecan
chondronectin

3

What forms the fibrillar component of the extracellular matrix of elastic cartilage?

type I collagen and elastic fibers
type II collagen and elastic fibers
type II collagen
elastic fibers

4

What forms the fibrillar component of the extracellular matrix of fibrocartilage?

type I and type II collagen
type I collagen
type III collagen
type II and type III collagen

5

Which type of cartilage forms the annulus fibrosus of the intervertebral disc?

hyaline cartilage
parenchymal cartilage
elastic cartilage
fibrocartilage

6

What forms the fibrous component of the extracellular matrix of primary bone?

type I collagen fibrils
type I collagen fibers
type II collagen fibrils
type II collagen fibers

7

What is the fate of most osteoblasts after they have produced a sufficient amount of extracellular matrix?

transformation into an osteoblast
transformation into an osteocyte
apoptosis
necrosis

8

What is osteoid?

immature bone extracellular matrix that does not yet contain a fibrous component
immature bone extracellular matrix that has not yet been mineralized
resorbed bone in which only the organic component has so far been degraded
resorbed bone in which only the mineral component has so far been degraded

9

What form does the inorganic component of the bone extracellular matrix take?

calcium bicarbonate crystals
calcium carbonate crystals
hydroxyapatite crystals
gypsum crystals

10

What are the two forms of lamellar bone?

chondrogenic and desmogenic bone
compact and spongy bone
primary and secondary bone
fibrous and plate-like bone

11

What are Sharpey's fibers?

bundles of collagen fibers extending from the periosteum into the bone
bundles of collagen fibers running within the endosteum
processes of osteocytes
trabeculae of trabecular bone

12

What are interstitial lamellae?

remnants of partially resorbed Haversian systems
lamellae formed by the periosteum and surrounding the entire bone
small lamellae surrounding Volkmann's canals
lamellae of complete Haversian systems

13

Long bones develop by remodeling a cartilaginous bone model. Which type of cartilage forms the cartilaginous model of long bones?

hyaline cartilage
elastic cartilage
fibrocartilage
it depends on the particular bone

14

In the hypertrophic zone of the growth plate, chondrocytes produce a type of collagen characteristic of this zone. Which one?

type III collagen
type IV collagen
type VII collagen
type X collagen

15

Which type of tissue connects two bones in symphyses?

hyaline cartilage
fibrocartilage
lamellar bone
woven bone