Histology MCQs/Blood and Hematopoiesis

1 Which function do have azurophilic granules in leukocytes?

	Derivatives of the smooth endoplasmic reticulum
	Derivatives of the cytoskeleton
	Cell inclusions
	Lysosomes

2 Diameter of basophilic erythroblast is:

	6 to 8 μm
	10 to 16 μm
	20 μm
	22 to 25 μm

3 Diameter of megakaryocyte is:

	5 to 20 μm
	20 to 50 μm
	50 to 150 μm
	150 to 1000 μm

4 Diameter of myeloblast is:

	1 to 5 μm
	5 to 10 μm
	10 to 15 μm
	15 to 20 μm

5 Diameter of orthochromatophilic erythroblast is:

	6 to 8 μm
	8 to 10 μm
	10 to 18 μm
	20 to 25 μm

6 Diameter of proerythroblast is:

	20 μm
	40 μm
	60 μm
	80 μm

7 What is a a differential blood count (leucogram):

	Relative frequency of all formed blood elements
	Absolute number of all formed blood elements
	Relative frequency of white blood cells
	Absolute number of white blood cells

8 What are dimensions of an average red blood cell?

	Diameter 7.5 μm, maximal thickness 2.6 μm, thickness in the middle 0.8 μm
	Diameter 10 μm, maximal thickness 1.6 μm, thickness in the middle 0.1 μm
	Diameter 7.5 μm, maximal thickness 1.6 μm, thickness in the middle 0.8 μm
	Diameter 10 μm, maximal thickness 2.6 μm, thickness in the middle 0.1 μm

9 Except one, all below mentioned cells are differentiated monocytes. Which of them is the exception?

	Microglia
	Osteoclast
	Goblet cell
	Kupfer's cell

10 How is called first morphologically distinguishable stage of development of red blood cells?

	Polychromatophilic erythroblast
	Ortochromatophilic erythroblast
	Basophilic erythroblast
	Proerythroblast

11 How many of basophils are in the blood?

	0 to 1 % of all WBC's
	3 to 5 % of all WBC's
	20 to 30 % of all WBC's
	60 to 70 % of all WBC's

12 How many of eosinophils are in the blood?

	0 to 1 % of all WBC's
	2 to 5 % of all WBC's
	20 to 30 % of all WBC's
	60 to 70 % of all WBC's

13 How many of lymphocytes are in the blood?

	3 to 5 % of all WBC's
	5 to 20 % of all WBC's
	20 to 40 % of all WBC's
	60 to 70 % of all WBC's

14 How many of monocytes are in the blood?

	1 to 3 % of all WBC's
	2 to 10 % of all WBC's
	20 to 30 % of all WBC's
	60 to 70 % of all WBC's

15 How many of neutrophilic bands are in the blood?

	0 to 1 % of all WBC's
	2 to 5 % of all WBC's
	60 to 70 % of all WBC's
	20 to 30 % of all WBC's

16 How many of neutrophils are in the blood?

	0 to 1 % of all WBC's
	3 to 5 % of all WBC's
	20 to 30 % of all WBC's
	60 to 70 % of all WBC's

17 How many platelets (trombocytes) are in the blood?

	15 000 to 40 000 in mm³
	150 000 to 400 000 in mm³
	1.5 000 000 to 4 000 000 in mm³
	15 000 000 to 40 000 000 in mm³

18 Which important compounds are inside specific granules of basophlis?

	Heparine a histamine
	Kolagenases
	Defensins
	Lysozym

19 In which stage occur changes of nuclear morphology which are hallmark of granulocytes?

	Metamyelocyte
	Promyelocyte
	Myeloblaste
	Myelocyte

20 In which stage starts production of specific granules?

	Metamyelocyte
	Promyelocyte
	Myeloblaste
	Myelocyte

21 Which stage of development of red blood cells is last stage sensitive to erythropoietin (EPO)?

	Polychromatophilic erythroblast
	Ortochromatophilic erythroblast
	Basophilic erythroblast
	Proerythroblast

22 Life-span of the red blood cell is around:

	3 to 5 days
	50 days
	80 days
	120 days

23 Main difference between the blood plasma and serum is:

	Plasma does not contain proteins involved in blood clotting
	Serum does not contain proteins involved in blood clotting
	Plasma does not contain albumin and prealbumin
	Serum does not contain albumin and prealbumin

24 Major basic protein (MBP) is main part of specific granules of:

	All granulocytes
	Neutrophlis
	Eosinophils
	Basophils

25 How is called pathological condition where red blood cells of pathological shapes are present?

	Poikilocytosis
	Anisocytosis
	Polycytaemia
	Anaemia

26 Platelets (trombocytes) are not assumed to be cells because:

	Bad formulation of the question, platelets are cells
	They are fragments of cytoplasm of the megakaryocyte
	It was states so in the past
	They have no nuclei

27 Which of following statements about platelets is not true?

	alpha (α) granules contain proteins involved in blood clotting
	delta (δ) granules contain ATP. ADP. serotonin and calcium
	lamda (λ) granules contain hydrolytic enzymes
	mu (µ) granules contain myeloperoxidase

28 In which structure is first site of production of red blood cells in the embryo?

	Wall of the yolk sack
	Bone marrow
	Kidney
	Liver

29 The best definition of the hematocrit (HCT) is:

	Volume percentage of the blood occupied by formed blood elements
	Mass percentage of the blood occupied by formed blood elements
	Total volume of the blood occupied by formed blood elements
	Total mass of the blood occupied by formed blood elements

30 Which anions are the most common in the blood plasma?

	SO42- a Cl-
	H2PO4- a HSiO4-
	Cl- a HCO3-
	HCO3- a HSiO4-

31 Which cation has the highest concentration in the blood plasma?

	Ca2+
	Mg2+
	Na+
	K+

32 Which is a diameter of the monocyte?

	6 to 8 μm
	10 to 12 μm
	12 to 20 μm
	16 to 18 μm

33 Which is a diameter of the neutrophil?

	6 to 8 μm
	10 to 12 μm
	12 to 20 μm
	16 to 18 μm

34 What is a leukocyte?

	Activated white blood cell
	Quiescent white blood cell
	Immature white blood cell
	Any white blood cell

35 What is main function of buffer systems in the blood?

	Blood buffer is curiosity of biophysical chemistry, but it is out of physiological importance
	They are involved in regulation of pH on value related to the actual need of the organism
	They are involved in regulation of pH on strict value
	There is nothing like buffers inside the blood

36 Which hormone or cytokine simulates formation of platelets?

	Trombopoietin
	Erytropoietin
	Interleukin 6
	Vasopresin

37 Which hormone or cytokine simulates formation of red blood cells?

	Erytropoietin (Epo)
	Interleukin 1 (IL 1)
	Interleukin 6 (IL 6)
	Vasopresin

38 Which hormone or cytokine simulates maturation of granulocytes?

	SCF (stem cell factor)
	Interleukin 5 (IL 5)
	Angiotensin
	GM-CSF

39 Which of below mentioned cells is not able to undergo mitosis?

	Orthochromatophilic erythroblast
	Polychromatophilic erythroblast
	Bazophilic erythroblast
	Proerythroblast

40 Which of following cells is the least differentiated?

	Metamyelocyte
	Promyelocyte
	Myeloblast
	Myelocyte

41 Which of statements below describes B lymphocytes the best?

	B lymphocytes has nucleus composed of lobules
	B lymphocytes are precursors of plasma cells
	B lymphocytes has fagocytic activity
	B lymphocytes produce antibodies

42 Which of statements below describes T lymphocytes the best?

	We have different types of T lymphocytes according to their function
	Mature T lymphocytes are released from the bone marrow
	T lymphocytes has nucleus composed of lobules
	T lymphocytes are usually two-nucleated

43 Which statement about development of the megakaryocyte is correct?

	It is a result of both endomitosis and fusion of precursor cells, but endomitosis dominates
	It is a result of both endomitosis and fusion of precursor cells, but fusion dominates
	It is a result of endomitotic division of precursor cell
	It is a result of fusion of precursor cells

44 Which statement about monocytes is false?

	Except in very exceptional cases. they have a round nucleus
	They circulate in the peripheral blood few days only
	They can differentiate in macrophages
	They have 15 to 20 μm in diameter

45 Which type of tissue serves as a supportive structure for hematopoiesis in the bone marrow?

	Jelly-like connective tissue
	Reticular connective tissue
	Elastic connective tissue
	Connective tissue proper

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