Genetics in presymptomatic diagnostics and prevention of cancer

From WikiLectures

  • To whom and under what conditions is it possible to offer genetic testing (genetic / ethical limitations)
  • Reasons of presymptomatic testing, clinical consequences of obtained genetic
  • Usual type of inheritance in hereditary cancer syndromes
  • Approaches of genetic analyses used in presymptomatic diagnostics
  • Definition of hereditary cancer syndrome, some examples of them (typical predisposing genes)
  • Characterization of typical cancer predisposition genes – their role in cell biology
  • Rationalization of the differences between hereditary and sporadic forms of carcinoma