Under construction / Forgotten
|
This article was marked by its author as Under construction, but the last edit is older than 30 days. If you want to edit this page, please try to contact its author first (you fill find him in the history). Watch the discussion as well. If the author will not continue in work, remove the template {{Under construction}} and edit the page. Last update: Saturday, 17 Dec 2022 at 9.12 pm.
|
This article has been translated from WikiSkripta; ready for the editor's review.
Metal ions and trace elements[edit | edit source]
Cofactor |
Examples of enzymes
|
Zn2+ |
Peptidases, alcohol dehydrogenase
|
Mg2+ |
ATP dependent enzymes, phosphohydrolases
|
Mn2+ |
Superoxide dismutase, arginase
|
Fe2+/ Fe3+ |
Cytochromes, catalase, peroxidases
|
Cu2+ |
Cytochrome oxidase, amino oxidase
|
Mo2+ |
Xanthine dehydrogenase
|
Cofactors of oxidoreductases[edit | edit source]
Cofactor |
Default vitamin |
Location/Function
|
ATP, GTP |
Thiamine (B1) |
Transfer of a phosphate residue
|
TDP (thiamine diphosphate) |
Thiamin (B1) |
Transfer of carbon fragments (oxidative decarboxylation)
|
PALP (pyridoxal phosphate) |
Pyridoxine (B6) |
Transfer of −NH2 groups (transamination), decarboxylation of amino acids
|
THF (tetrahydrofolate) |
Folate (folic acid) |
Transfer of one-carbon fragments
|
CoA (coenzyme A) |
Pantothenate |
Acyl transfer
|
PAPS (phosphoadenosine phosphosulfate) |
|
Sulfate transfer
|
SAM (S-adenosylmethionine) |
|
Methylation
|
B12-complex |
Cobalamin B12 |
Transfer of the CH3 group
|
Cofactor |
Default vitamin |
Location/Function
|
PALP (pyridoxal phosphate) |
Pyridoxine (B6) |
Decarboxylation
|
Cofactor |
Default vitamin |
Location/Function
|
ATP |
|
|
Carboxybiotin |
Biotin |
CO2 transfer (carboxylation)
|