Enterovirus diseases
From WikiLectures
Enteroviruses[edit | edit source]
- They occur worldwide, causing diseases very often .
- together with rinoviruses and aphtoviruses, they belong to the RNA family Picornaviridae.
- Divided into:
- Polioviruses,
- Coxsackie,
- ECHO viruses.
- EV 68 − 71[1]
Source of infection and symptoms[edit | edit source]
- Human, transmission mainly by the fecal-oral route;
- often in summer;
- most often infected – preschool children;
- place of multiplication – nasopharyngeal mucosa, tonsils or small intestine → nodules→ primary viremia→ into various organs, multiply→ secondary viremia;
- the most prominent pathogenic property – neurotropicity (mainly polioviruses);
- myotropicity (coxsackie) – myositis, dermotropicity;
- the infection can be stopped at various levels by immunity – often at the site of the first multiplication,
- long-term immunity develops after infection;
- clinical manifestations are very varied, about 90 % are inapparent;
- the same serotype may cause completely different symptoms in different individuals (ECHO9 may cause serous meningitis in one fever, serous menigitis in another, and rash in another);
- EV 70 is one of the causes of acute hemorragic conjunctivitis[2]
- EV 71 is one of the causative agents of aseptic meningitis, encephalitis, polyneuritis and respiratory disesases[3]
