Concentration of ketones in plasma

From WikiLectures

Here is an overview of the plasma concentrations of 3-hydroxybutyrate (3-HB) in different situations:

Concentration of 3−hydroxybutyrate in plasma Concentration of free fatty acids (FFA) in plasma
After a meal ~ 0.05 mmol/l < 0.2 mmol/l
12-hour fasting < 0.2 mmol/l ~ 0.4 mmol/l
21-day fasting ~ 5.0 mmol/l ~ 1.5 mmol/l
T1DM; ketoacidosis; pH = 7.0 ~ 20.0 mmol/l ~ 5.0 mmol/l

The maximum rate of formation of ketone bodies is reached at a plasma concentration of ~ 12 mmol/l.

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  • RYBKA, Jaroslav. Diabetes mellitus : Komplikace a přidružená onemocnění. E-book edition. Grada, 2007. pp. 317. ISBN 978-80-247-1671-8.