CAMP (biochemistry)
From WikiLectures
Genesis[edit | edit source]
It is formed from ATP through an enzyme adenylyl cyclase.
Meaning[edit | edit source]
cAMP (cyklic 3´,5´-adenosine monophosphate) is used as one of the second messengers in cell signaling. Its activating effect on the enzyme protein kinase A is important.
Degradation[edit | edit source]
cAMP is degradated through an enzyme phosphodiesterase. This enzyme hydrolyzes its phosphodiester bond and thereby changes it to the physiologically ineffective form adenosine-5'-monophosphate (AMP).
It is one of the ways of regulating the transfer of information through the regulation of the concentrations of second messengers in the cytoplasm.
Links[edit | edit source]
Related articles[edit | edit source]
References[edit | edit source]
- SILBERNAGL, Stefan a Agamemnon DESPOPOULOS. Atlas fyziologie člověka. 6. vydání. Praha : Grada, 2004. 435 s. ISBN 80-247-0630-X.
