File:Activation protein kinase C.svg

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Summary

Description
English: activation of the protein kinase C by the phosphatidylinositol 4,5-bisphosphate (PIP2)-pathway involving phospholipase C (PLC) and DAG (diacyl glycerol). It starts with activation of an alpha-1 (α1) adrenergic G protein-coupled receptor (GPCR)
Deutsch: Aktivierung der Proteinkinase C durch den Phosphatidylinositol-4,5-bisphosphat (PIP2)-Weg: Ein Hormonsignal aktiviert einen G-Protein-gekoppelter Rezeptor (α1-Adrenozeptor), wodurch die aktivierte alpha-Untereinheit von Gq eine Phosholipase C (PLC) stimuliert. Diese hydrolysiert PIP2 zu Inositol und dem korrespondierenden Diacylglycerin (DAG). An letzteres bindet plasmamembranassoziierte Proteinkinase C und wird dadurch aktiviert.
Date
Source Own work; ISBN 978-3-8273-7312-0; ISBN 978-0781798754
Author Yikrazuul

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Captions

A schematic of the intracellular signaling pathway that activates protein kinase C.

inception

4 July 2010

media type

image/svg+xml

checksum

3145800de2f68df17e8adc1814e6d940e43f06ae

determination method: SHA-1

data size

187,776 byte

height

480 pixel

width

1,020 pixel

File history

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