Occipital arteritis
thumb|200px|Takayasuova arteritida thumb|right|200px|Takayasuova arteritida u 18-ti měsíčního dítěte manifestující se mozkovým aneuryzmatem Takayasu's arteritis is a chronic vasculitis of unknown etiology affecting mainly the aorta , its main branches and pulmonary arteries. Damage to the vessel wall leads to stenoses, blockages and the formation of aneurysms . It occurs mainly in women under 40 years of age, the endemic area is Southeast Asia. This disease was first described by the Japanese ophthalmologist Mikito Takayasu.
Clinical picture[edit | edit source]
The disease typically occurs in 2 phases:
- nonspecific phase (systemic): fever, weight loss, fatigue, weakness, myalgia, arthralgia, Raynaud's phenomenon , recurrent infection, recurrent iritis;
- specific phase (vascular occlusive): systolic murmurs , absence of peripheral pulsations, signs of ischemia of affected areas, hypertension , cardiomyopathy , aortic valve involvement, etc.
Diagnostics[edit | edit source]
Physical examination[edit | edit source]
- weakening of the pulse / murmur over the large arteries, different values of blood pressure in the upper limbs.
Laboratory[edit | edit source]
- ↑ CRP + FW , anemia with leukocytosis.
Display methods[edit | edit source]
- USG, aortography, angiography, CT-angio, MRI (segmental narrowing of large arteries / microaneurysms of the vessel wall).
Treatment[edit | edit source]
Treatment is based on the administration of corticosteroids . In unresponsive patients, corticosteroids are combined with immunosuppressants (cyclophosphamide, methotrexate, azathioprine). Proper correction of hypertension and symptomatic treatment are also essential. We treat stenoses and closures using PTA or surgery.
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Související články[edit | edit source]
Použitá literatura[edit | edit source]
Kategorie:Vnitřní lékařství Kategorie:Angiologie Kategorie:Patologie